• Progressive Motor and Non-Motor Symptoms in Park7 Knockout Zebrafish 

      Chavali, Lakshmi Narasimha Murthy; Yddal, Ingeborg; Bifulco, Ersilia; Mannsåker, Simen; Røise, Dagne; Law, Jack Owen; Frøyset, Ann Kristin; Grellscheid, Sushma Nagaraja; Fladmark, Kari Espolin (Journal article; Peer reviewed, 2023)
      DJ-1 is a redox sensitive protein with a wide range of functions related to oxidative stress protection. Mutations in the park7 gene, which codes for DJ-1 are associated with early onset familial Parkinson’s disease and ...
    • Reintroduction of dj-1 in müller cells inhibits retinal degeneration in the dj-1 deficient retina 

      Gharbi, Naouel; Røise, Dagne; Førre, Jorunn-Elise; Edson, Amanda Jayne; Hushagen, Helena Amalie; Tronci, Valentina; Frøyset, Ann-Kristin; Fladmark, Kari E. (Journal article; Peer reviewed, 2021)
      The eye is continuously under oxidative stress due to high metabolic activity and reactive oxygen species generated by daily light exposure. The redox-sensitive protein DJ-1 has proven to be essential in order to protect ...